Cardiac and renal damage in the elderly hypertensive.
نویسندگان
چکیده
منابع مشابه
Hypertensive target-organ damage in the very elderly.
In people aged >80 years, the so-called very elderly, there is uncertainty about the relation between hypertension and cardiovascular morbidity. The aims of this study were to investigate whether hypertension in people aged >80 years is associated with target-organ damage, over and above the effects of age, and to determine whether ambulatory blood pressure monitoring (ABPM) could improve on co...
متن کاملThe controllability of cardiac rhythm in elderly
Introduction: Recent reports have shown that rare fluctuations in cardiac cycles are ‘forgotten’ quickly in healthy individuals and it is possible to quantify the “memory length” of a physiological time-series using an inverse statistical approach. Methods: In the present study, we assessed the effect of aging on memory length in cardiac rhythm. Results: There was a long...
متن کاملGenetic Susceptibility to Hypertensive Renal Damage
To test the hypothesis that genetic factors can determine susceptibility to hypertension-induced renal damage, we derived an experimental animal model in which two genetically different yet histocompatible kidneys are chronically and simultaneously exposed to the same blood pressure profile and metabolic environment within the same host. Kidneys from normotensive Brown Norway rats were transpla...
متن کاملRelaxin reverses cardiac and renal fibrosis in spontaneously hypertensive rats.
The antifibrotic effects of the peptide hormone relaxin on cardiac and renal fibrosis were studied in 9- to 10-month-old male spontaneously hypertensive rats (SHR) and normotensive Wistar-Kyoto rats (WKY). Rats (n=8 to 9 per group) were allocated into 3 groups: WKY controls, vehicle-treated SHR (SHR-V), and relaxin-treated SHR (SHR-R). Relaxin (0.5 mg/kg per day) was administered via subcutaneo...
متن کاملRenal vascular dysfunction precedes the development of renal damage in the hypertensive Fawn-Hooded rat.
It is unknown whether generalized vascular dysfunction precedes the development of kidney disease. Therefore, we studied myogenic constriction and endothelium-mediated dilatory responses in two inbred Fawn-Hooded (FH) rat strains, one of which spontaneously develops hypertension, proteinuria, and glomerulosclerosis (FHH), whereas the other (FHL) does not. Small renal, mesenteric resistance arte...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of the renin-angiotensin-aldosterone system : JRAAS
سال: 2002
ISSN: 1470-3203
DOI: 10.3317/jraas.2002.026